Hatice Sultan

She is the youngest daughter of Hafsa Sultan and Sultan Selim I. She is the younger sister of Sultan Suleiman I. She is considered one of the most important characters at the start of the series.

Originally, a rather self-effacing character, she gradually reveals herself in a new light; indeed, she is in love with Pargali Ibrahim Pacha, her brother's best friend, feelings which are shared entirely by Ibrahim. Her romance will define her throughout her life and the series. First considered a fair and upright sultana, the young Hatice is very close to Hürrem Sultan who promises to help her in his desire to marry Ibrahim, and despite the ups and downs in this relationship, they have remained fairly close during the first two seasons, until finally opposing at the end of second season. Hürrem will even help her to marry her lover, then save the life of her first child, which will create quite a strong bond between them, and despite Hürrem's betrayals, the two women have always respected each other.

Nevertheless, gradually, Hatice ends up getting accustomed to the intrigues, the betrayals and the dangerous games of the harem, and after the revelation made by Hürrem on the infidelity of Ibrahim, the latter becomes the person to be slaughtered for the sultana. Hatice tries by all means to take revenge on his brother's wife for putting her in this shameful and dishonorable situation. She then surrounds herself with Gülfem Hatun, Mahidevran Sultan, and later her sister Sah Sultan to help her in her revenge. But following the death of her husband Ibrahim, she refuses to mourn him without avenging his death, and then decides to devote her life to destroying Hürrem's whom she considers responsible for his death, while she has nothing to do with it. The feud between the two women is such that Suleiman is forced to intervene and forces his sister to marry Hüsrev Pacha, a member of his council, as a third marriage. Despite everything, all means are good to take revenge on Hürrem, and madness gets the better of his morals. She ends up having her enemy kidnapped thanks to an ingenious stratagem. When Suleiman discovers that she is at the heart of this matter and he goes to her house to ask ker for answers, she decides to kill herself, and to take the truth to the grave, thus avenging her husband and avenging herself.

Main antagonist of the third season, she even continues to be talked about several years after her death, when her daughter Hurichian Sultan moved to Topkapi.

Great friend of Gülfem Hatun, and the adored daughter of her mother, Hatice Sultan is also very close to her nephew Sehzade Mustafa and Mahidevran Sultan. However, she is in open opposition with her niece Mihrimah.